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Practice targeted AMC-style multiple-choice questions on general practice.

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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with abdominal distension, obstipation, and vomiting. He has a history of prior abdominal surgery. An upright abdominal X-ray is performed. What is the MOST appropriate next step in management?

A. Colonoscopy
B. Surgical consultation
C. Barium enema
D. Stool softeners
E. Oral antibiotics
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male with a history of smoking and hyperlipidemia presents for a health check. He is asymptomatic. A contrast-enhanced CT abdomen is performed as part of a screening protocol. An axial view is shown. Besides optimizing medical management, what is the MOST appropriate next step?

A. Repeat imaging in 6-12 months
B. Referral for immediate surgical repair
C. Initiate dual antiplatelet therapy
D. Prescribe a short course of oral corticosteroids
E. Order a D-dimer to rule out acute thrombosis
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A GP working in a hospital is observed getting into arguments with colleagues. Later, a colleague finds her disoriented and walking in the hallway. What is the most appropriate initial step?

A. Assume it is a personal matter and take no immediate action.
B. Advise the GP to go home and rest.
C. Talk to the GP privately to understand the issue.
D. Document the observations in the GP's personnel file.
E. Notify a superior or relevant authority (e.g., medical supervisor, head of department).
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A 62-year-old male presents to his general practitioner with a six-month history of a painless bulge in his right groin. On examination, a soft swelling is palpable in the right inguinal region, which increases in size on coughing or straining. The swelling is located medial to the inferior epigastric vessels. Which of the following is the most appropriate initial management strategy according to current Australian guidelines?

A. Reassurance and watchful waiting, with advice to return if symptoms worsen.
B. Urgent referral to an emergency department for exclusion of strangulation.
C. Prescription of a truss to provide symptomatic relief.
D. Referral to a physiotherapist for core strengthening exercises.
E. Referral to a general surgeon for consideration of elective repair.
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A 28-year-old woman with a mother diagnosed with colorectal cancer at 45 and a maternal uncle at 50 seeks advice. She is otherwise well. What is the most appropriate next step in her management?

A. Annual FIT testing.
B. Consider prophylactic colectomy.
C. Genetic counselling and testing.
D. Colonoscopy screening at 40.
E. Reassurance and review.
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Umbilical hernia
Image by Ibrahim Husain Meraj CC BY-SA 4.0 · Source

A 3-year-old child is presented to the general practitioner by their parents who are concerned about the appearance of their child's umbilicus, as depicted in the accompanying image. The child is reported to be entirely asymptomatic, feeding and playing normally, with no history of pain, discomfort, or vomiting. Physical examination reveals normal vital signs and a soft, non-tender abdomen with no signs of obstruction. Considering the clinical presentation and the finding shown, what is the most appropriate initial management plan for this child?

A. Order an abdominal ultrasound scan to evaluate the contents and size of the defect.
B. Arrange an urgent consultation with a paediatric surgeon for immediate operative repair.
C. Prescribe a course of simple analgesia and schedule a routine follow-up appointment in one week.
D. Recommend the application of a firm abdominal binder or tape over the affected area to prevent enlargement.
E. Provide reassurance to the parents regarding the benign nature and likelihood of spontaneous resolution, advising them on signs requiring further assessment.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with left lower quadrant pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed, the axial view is shown. What is the most appropriate next step in management?

A. Order a barium enema to assess for fistula
B. Prescribe oral antibiotics and a high-fiber diet
C. Perform a colonoscopy to rule out malignancy
D. Schedule elective sigmoid colectomy
E. Initiate intravenous antibiotics and bowel rest
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A 23-year-old backpacker doing farm work presents with a low-grade fever for 4 days. Q fever is suspected. What is the most appropriate diagnostic method for acute Q fever in Australia?

A. Chest X-ray
B. Serology (IFA for Phase II antibodies)
C. Serum PCR for C. burnetii.
D. Rapid antigen test for C. burnetii.
E. Serial blood cultures
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash that started a few weeks ago. She reports that it began on her wrists and ankles and has now spread to her elbows and knees. She denies any new medications, travel, or changes in personal care products. On examination, you observe symmetrical, excoriated papules and plaques on her wrists, elbows, knees, and upper back. Some of the papules have small blisters. Which of the following is the most appropriate initial investigation?

A. Patch testing with a standard allergen series
B. Potassium hydroxide (KOH) examination of skin scraping
C. Serum IgE level
D. Skin biopsy for direct immunofluorescence
E. Viral culture of blister fluid
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A 50-year-old Aboriginal man presents for a routine check. He has a history of smoking and lives in a remote community. What screening is most important to address his increased risk?

A. Cardiovascular risk assessment and diabetes screening
B. Glaucoma screening
C. Prostate cancer screening
D. Vitamin D deficiency screening
E. Osteoporosis screening
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents with constant RUQ pain for 3 days. The image was obtained. What is the MOST likely complication if definitive management is delayed?

A. Hepatic abscess
B. Pancreatitis
C. Gallbladder perforation
D. Choledocholithiasis
E. Ascending cholangitis
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A 40-year-old Aboriginal man presents for a health check. He has a strong family history of diabetes and cardiovascular disease. What is the most appropriate initial screening test to assess his risk?

A. Liver function tests
B. Urine analysis
C. Fasting blood glucose and lipid profile
D. Full blood count
E. ECG
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old male presents with a painful, irreducible right groin mass. He reports vomiting and abdominal distension. His vitals are: HR 110, BP 100/60, RR 22, SpO2 96% RA. The provided image was obtained. What is the next step?

A. Attempt manual reduction with sedation
B. Surgical consultation for emergent repair
C. Order a repeat CT scan with contrast in 6 hours
D. Start a clear liquid diet
E. Administer intravenous antibiotics
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old male presents with groin pain and vomiting. The provided image was taken. What is the most appropriate next step in management?

A. Discharge with stool softeners
B. Administer intravenous antibiotics
C. Apply ice packs to the groin
D. Start a clear liquid diet
E. Surgical consultation for possible bowel resection
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 59-year-old male presents with a painful right groin bulge that has progressively worsened over the past week. He denies fever, chills, nausea, or vomiting. Vitals are stable. The provided image was obtained. What is the MOST appropriate next step?

A. Prescribe analgesics and discharge with surgical follow-up
B. Order a bowel preparation
C. Attempt manual reduction with sedation
D. Initiate broad-spectrum antibiotics
E. Surgical consultation for operative management
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 62-year-old man presents to his GP with a history of a bulge in his right groin that has been present for approximately 18 months. He reports it is more prominent with straining or standing and disappears completely when he lies down. He denies any associated pain, nausea, vomiting, or change in bowel habits. He has no significant past medical history. His physical examination reveals the finding depicted in the image. Vital signs are within normal limits. Based on this clinical picture, which of the following represents the most appropriate definitive management strategy for this patient?

A. Observation with regular follow-up.
B. Urgent surgical exploration.
C. Further imaging to confirm the diagnosis.
D. Elective surgical repair.
E. Non-surgical management with a supportive device.
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Acute cholecystitis with gallbladder wall thickening, a large gallstone, and a large gallbladder
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 45-year-old female presents to the emergency department with a 3-day history of right upper quadrant pain, nausea, and subjective fevers. She reports that the pain is constant and worsened by eating. She has no significant past medical history and takes no medications. On examination, she is noted to be uncomfortable, with a temperature of 38.2°C, heart rate of 110 bpm, blood pressure of 130/80 mmHg, and an oxygen saturation of 99% on room air. Abdominal examination reveals marked tenderness to palpation in the right upper quadrant with guarding. Murphy's sign is positive. Laboratory investigations reveal a white blood cell count of 15,000/µL with neutrophilic predominance, total bilirubin of 1.8 mg/dL, alkaline phosphatase of 280 U/L, ALT of 160 U/L, and AST of 130 U/L. The provided image was obtained. Considering the clinical presentation and the findings on the image, which of the following is the MOST appropriate next step in management?

A. Order a hepatobiliary iminodiacetic acid (HIDA) scan
B. Administer analgesics and antiemetics, and discharge home with outpatient follow-up
C. Perform an ERCP to rule out choledocholithiasis
D. Initiate intravenous antibiotics and observe for 48 hours
E. Surgical consultation for cholecystectomy
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man presents to his GP with a 3-month history of intermittent lower back pain, which is worse with activity. He has a history of hypertension, hyperlipidaemia, and is a former smoker. Physical examination reveals normal vital signs and no abdominal tenderness or pulsatile mass. Routine blood tests are normal. An abdominal CT scan is performed as part of the workup. Considering the findings demonstrated in the image, what is the most appropriate next step in the management of this patient?

A. Prescribe analgesia and review in 3 months.
B. Advise no further imaging is necessary.
C. Schedule surveillance ultrasound in 12 months.
D. Refer for urgent vascular surgical consultation.
E. Arrange a repeat CT scan in 6 months.
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Umbilical hernia
Image by Ibrahim Husain Meraj CC BY-SA 4.0 · Source

A 14-month-old child is presented to the general practitioner by their parents, who are concerned about a noticeable protrusion around the navel. They report this bulge is more prominent when the child cries or strains but easily disappears when the child is relaxed or sleeping. There are no reports of pain, discomfort, changes in bowel habits, or feeding difficulties. The child is meeting all developmental milestones and appears well. On examination, vital signs are stable and within age-appropriate ranges. The abdomen is soft and non-tender, with no distension. The finding illustrated in the accompanying image is observed. Based on this clinical presentation and examination, what is the most appropriate initial management plan?

A. Refer the child urgently to a paediatric surgeon for immediate assessment and potential repair.
B. Recommend applying a specific binder or tape over the area to facilitate closure.
C. Provide reassurance to the parents regarding the benign nature of the finding and advise observation, explaining the high likelihood of spontaneous resolution by school age.
D. Advise the parents to present immediately to the nearest emergency department if the bulge is visible.
E. Order an abdominal ultrasound to assess the contents and size of the defect.
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A 52-year-old woman presents to her GP with a palpable lump in her right breast. She reports no pain, nipple discharge, or skin changes. She has no family history of breast cancer. On examination, the lump is firm, non-tender, and mobile. There is no axillary lymphadenopathy. What is the most appropriate initial investigation?

A. Breast ultrasound
B. Mammography
C. Fine-needle aspiration (FNA)
D. MRI of the breast
E. Core biopsy
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A patient on warfarin presents with leg pain. INR is 3.5. Given the image, what is the MOST appropriate next step?

A. Stop warfarin and administer vitamin K
B. Elevate the leg and apply warm compresses
C. Continue warfarin at the same dose
D. Apply topical corticosteroids
E. Start heparin and continue warfarin
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A 45-year-old man presents to the clinic with a 3-month history of fatigue, weight loss, and abdominal pain. He has a history of type 2 diabetes and hypertension. On examination, he has a palpable mass in the left upper quadrant of the abdomen. Laboratory tests reveal anemia and elevated serum lactate dehydrogenase (LDH). A CT scan of the abdomen shows splenomegaly and multiple hypodense lesions in the spleen. What is the most likely diagnosis?

A. Splenic lymphoma
B. Renal cell carcinoma with splenic metastasis
C. Chronic pancreatitis
D. Infectious mononucleosis
E. Portal hypertension
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A 56-year-old gentleman, a gardener and cat owner, presents with 24 hours of pain, swelling, and redness on his right index finger. His temperature is 38.1°C and pulse is 72. Suspected gout. What is the most appropriate next step?

A. Aspirate joint for microscopy and culture.
B. Urgent hospital referral for drainage and IV antibiotics.
C. Prescribe oral antibiotics and review in 24 hours.
D. Start diclofenac TDS and discuss allopurinol.
E. Order serum uric acid level.
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old man presents to his GP with a lesion on his nose that has been present for several months and seems to be slowly enlarging. He denies pain, itching, or bleeding. He works outdoors but reports using sunscreen inconsistently. His past medical history is unremarkable, and he takes no regular medications. On examination, vital signs are stable. Regional lymph nodes are not palpable. The lesion is as shown in the image. Considering the clinical presentation, risk factors, and the appearance of the lesion, which of the following represents the most appropriate initial step in establishing a definitive diagnosis and guiding management?

A. Referral for cryotherapy
B. Application of topical corticosteroid cream twice daily
C. Punch biopsy for bacterial culture and sensitivity
D. Excisional or incisional biopsy for histological examination
E. Reassurance and review in three months
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 55-year-old man presents to his GP with a persistent lesion on his nose that has been present for several months and has not changed significantly in size or appearance. He reports it is occasionally itchy but otherwise asymptomatic. His medical history is unremarkable, and vital signs are within normal limits. On examination, you observe the lesion shown in the image. Considering the appearance of this lesion, what is the most appropriate initial step in the management of this patient?

A. Perform a punch or shave biopsy of the lesion.
B. Advise watchful waiting and review in 6 months if it changes.
C. Prescribe a 7-day course of oral flucloxacillin.
D. Initiate treatment with topical hydrocortisone 1%.
E. Refer for Mohs micrographic surgery.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 58-year-old male presents with left lower quadrant abdominal pain and a low-grade fever. The provided image was obtained. What is the most likely diagnosis?

A. Ovarian cyst
B. Sigmoid volvulus
C. Diverticulitis
D. Appendicitis
E. Ulcerative colitis
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes no medications and reports no significant past medical history. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Liver function tests
B. Prolactin level
C. Mammography
D. Serum testosterone and estradiol levels
E. Fine needle aspiration
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A 67-year-old woman presents to her GP with fatigue, weight loss, and night sweats over the past two months. She has a history of smoking and hypertension. On examination, she has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal a hemoglobin level of 10 g/dL, elevated lactate dehydrogenase (LDH), and a peripheral blood smear showing atypical lymphocytes. What is the most likely diagnosis?

A. Non-Hodgkin's lymphoma
B. Multiple myeloma
C. Hodgkin's lymphoma
D. Chronic lymphocytic leukemia (CLL)
E. Acute myeloid leukemia (AML)
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 30-year-old recent immigrant from a high-TB prevalence country presents with a persistent cough and night sweats for 2 months. Sputum cultures are negative for acid-fast bacilli. A PET-CT scan was performed, and an image is shown. What is the MOST appropriate next step in management?

A. Repeat sputum cultures in one week
B. Initiate anti-tuberculosis therapy
C. Prescribe a course of broad-spectrum antibiotics
D. Order a bronchoscopy with biopsy
E. Start the patient on corticosteroids
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A 45-year-old farmer presents with a 10-day history of fever, severe retro-orbital headache, and myalgia. He denies cough or dyspnoea. Physical examination is unremarkable. What is the most appropriate initial investigation?

A. Liver function tests
B. Serology for Coxiella burnetii
C. Chest X-ray
D. Blood culture
E. PCR for Coxiella burnetii
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Inguinal hernia right view. Adult male with an inguinal hernia, showing bulging in the groin area.
Image by IkeTheSloth CC0 1.0 · Source

A 60-year-old man presents with a reducible right groin bulge, as seen in the image. He reports mild discomfort. What is the most appropriate initial management?

A. Surgical referral for elective repair
B. CT scan of the abdomen and pelvis
C. Prescription of a truss support
D. Reassurance and watchful waiting
E. Strong analgesia and urgent surgical review
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A 28-year-old woman presents to her GP with a 3-month history of amenorrhea. She reports occasional headaches and galactorrhea. She is not on any medications and has no significant past medical history. On examination, her vital signs are normal, and there are no visual field defects. A pregnancy test is negative. What is the most appropriate initial investigation?

A. MRI of the brain
B. Serum prolactin level
C. Thyroid function tests
D. FSH and LH levels
E. Pelvic ultrasound
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A 22-year-old lady was wrongly given a B12 prescription for another patient. The error was noticed later at the pharmacy. What is the next step?

A. Notify the practice manager.
B. Report to AHPRA.
C. Apologize to the patient for the error.
D. Review practice procedures.
E. Document in patient notes.
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old man presents with bilateral breast enlargement, as shown. He denies pain or nipple discharge. What is the MOST likely underlying cause?

A. Liver cirrhosis
B. Medication side effect
C. Hyperthyroidism
D. Klinefelter syndrome
E. Testicular cancer
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Right leg affected by warfarin necrosis
Image by Bakoyiannis C, Karaolanis G, Patelis N, Maskanakis A, Tsaples G, Klonaris C, Georgopoulos S, Liakakos T CC BY 4.0 · Source

A patient on warfarin presents with leg pain. INR is 3.5. Given the image, what is the MOST likely underlying cause?

A. Antithrombin III deficiency
B. Factor V Leiden mutation
C. Protein C deficiency
D. Protein S deficiency
E. Prothrombin G20210A mutation
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A 50-year-old woman with a breast lump undergoes a mammogram, which shows microcalcifications. A core biopsy confirms ductal carcinoma in situ (DCIS). What is the most appropriate next step?

A. Start chemotherapy.
B. Perform a mastectomy.
C. Observe with repeat imaging in 6 months.
D. Perform a lumpectomy with radiation.
E. Start tamoxifen.
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for a routine health check. She reports intermittent episodes of colicky abdominal pain over the past year, which have since resolved. An abdominal ultrasound, as shown, was performed. Liver function tests are normal. Which of the following is the MOST appropriate next step in management?

A. Ursodeoxycholic acid therapy
B. Hepatobiliary iminodiacetic acid (HIDA) scan
C. Referral for elective cholecystectomy
D. Observation with repeat ultrasound in 6 months
E. ERCP with sphincterotomy
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A 40-year-old Aboriginal man presents for a health check. He reports feeling well but has a strong family history of diabetes and cardiovascular disease. What is the most appropriate initial screening test?

A. PSA
B. Full blood count
C. Fasting blood glucose and lipid profile
D. ECG
E. Urine albumin creatinine ratio
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 62-year-old male presents with acute onset of LLQ pain, fever, and vomiting. His WBC count is elevated. A CT scan of the abdomen and pelvis is performed. Based on the image, what is the most appropriate next step in management?

A. Flexible sigmoidoscopy
B. IV antibiotics and bowel rest
C. Stool softeners
D. Surgical resection
E. High-fiber diet
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 50-year-old man presents with a slowly growing nasal lesion. Examination reveals the image shown. What is the MOST appropriate initial management?

A. Excisional biopsy
B. Topical corticosteroids
C. Observation
D. Imiquimod cream
E. Cryotherapy
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A 35-year-old man presents to the clinic with a 3-month history of fatigue, weight loss, and night sweats. He also reports a persistent cough that has recently become productive of blood-streaked sputum. He has no significant past medical history and is not on any medications. He recently returned from a trip to Southeast Asia. On examination, he is febrile and has bilateral crackles in the upper lung fields. A chest X-ray shows cavitary lesions in the upper lobes. What is the most likely diagnosis?

A. Community-acquired pneumonia
B. Chronic obstructive pulmonary disease (COPD)
C. Lung cancer
D. Sarcoidosis
E. Pulmonary tuberculosis
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 45-year-old man presents to his GP with a lesion on his nose that he first noticed about 6 months ago. It has slowly increased in size but is not painful or itchy. He has no significant past medical history and takes no regular medications. On examination, vital signs are stable. The image shows the appearance of the lesion. Considering the clinical presentation and the appearance of the lesion shown, what is the most appropriate initial management step?

A. Reassure the patient and review in 3 months.
B. Excisional biopsy for histological assessment.
C. Prescribe a course of topical corticosteroid cream.
D. Refer immediately for Mohs micrographic surgery.
E. Arrange for cryotherapy in the clinic.
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A 35-year-old Aboriginal woman presents for a routine health check. She reports feeling tired lately and sometimes short of breath on exertion. She has a history of type 2 diabetes diagnosed 5 years ago, managed with metformin 500mg twice daily, and untreated hypertension. On examination, her blood pressure is 145/90 mmHg. Urinalysis shows 2+ protein. Blood tests reveal creatinine 180 µmol/L, eGFR 35 mL/min/1.73m², HbA1c 8.5%, potassium 4.2 mmol/L. Given these findings, which of the following is the most appropriate initial management step?

A. Increase the dose of metformin.
B. Prescribe a loop diuretic for fluid overload.
C. Advise dietary protein restriction only.
D. Initiate an ACE inhibitor or ARB and optimise blood pressure control.
E. Refer immediately for renal biopsy.
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents with a history of colicky pain. An ultrasound was performed. What is the MOST appropriate next step in management?

A. Start a low-fat diet
B. Surgical consultation for cholecystectomy
C. Endoscopic retrograde cholangiopancreatography (ERCP)
D. Administer ursodeoxycholic acid
E. Repeat ultrasound in 6 months
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PET-CT of a tuberculoma
Image by Annemie Snoeckx, Pieter Reyntiens, Damien Desbuquoit, Maarten J. Spinhoven, Paul E. Van Schil, Jan P. van Meerbeeck, Paul M. Parizel CC BY 4.0 · Source

A 45-year-old male, who recently immigrated from India, presents to his primary care physician with a two-month history of progressive fatigue, unintentional weight loss of 7 kg, and intermittent night sweats. He denies any cough, chest pain, or shortness of breath. He has no significant past medical history and is not currently taking any medications. Physical examination reveals normal vital signs, including a temperature of 37.1°C, and clear breath sounds bilaterally. However, mild cervical lymphadenopathy is noted. Initial laboratory investigations, including a complete blood count and comprehensive metabolic panel, are unremarkable. A chest X-ray reveals a solitary pulmonary nodule in the right upper lobe, which prompts a PET-CT scan for further evaluation. An axial slice from the PET-CT is shown. Given the patient's clinical presentation, immigration history, and the PET-CT findings, which of the following is the MOST appropriate next step in establishing a definitive diagnosis?

A. Bronchoscopy with transbronchial needle aspiration of the lesion
B. Administer a purified protein derivative (PPD) skin test
C. Order a CT-guided percutaneous needle biopsy of the lung nodule
D. Repeat PET-CT scan in three months to assess for interval growth
E. Initiate empiric antibiotic therapy with a broad-spectrum antibiotic
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Umbilical hernia
Image by Ibrahim Husain Meraj CC BY-SA 4.0 · Source

A 14-month-old child is brought to the general practitioner for a routine check-up and immunisations. The parents express mild concern about a bulge they have noticed around the child's navel, which seems more prominent when the child is crying or straining. They report it is easily pushed back in and does not appear to cause the child any pain or discomfort. The child is otherwise thriving, with normal feeding, bowel movements, and developmental progress. On physical examination, the child is alert and interactive. Vital signs are within normal limits for age. Abdominal examination reveals no distension or tenderness. The finding shown in the image is noted. Based on this clinical presentation and examination finding, what is the most appropriate initial management plan?

A. Provide reassurance to the parents that spontaneous closure is likely and no immediate intervention is required.
B. Arrange an abdominal ultrasound to assess the size of the fascial defect and contents of the sac.
C. Schedule elective surgical repair within the next 6 months to prevent future complications.
D. Recommend applying a firm abdominal binder or tape over the area to facilitate closure.
E. Refer the child for urgent surgical consultation due to the risk of incarceration or strangulation.
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66-year-old man, smoker with mild COPD, on salbutamol and tiotropium, confused regarding usage. Back for GPMP. Care plan?

A. Recommend zoster and pneumococcal vaccines.
B. Increase salbutamol dose.
C. Advise to cut down on smoking.
D. Recommend flu, COVID, and pneumococcal vaccines.
E. Refer for pulmonary function tests.
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman presents for a routine health check. She reports intermittent episodes of colicky abdominal pain over the past year, but denies any current pain, jaundice, or fever. An abdominal ultrasound is performed, the image is shown. What is the MOST appropriate next step in management?

A. Administer ursodeoxycholic acid
B. Discharge with reassurance
C. Initiate a low-fat diet
D. Referral for elective cholecystectomy
E. Order a HIDA scan
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A 45-year-old man presents to his general practitioner with a 3-month history of persistent cough and occasional wheezing. He is a non-smoker and works as a carpenter. He reports that his symptoms worsen at work and improve on weekends. He has no significant past medical history and is not on any medications. What is the most likely diagnosis?

A. Viral upper respiratory tract infection
B. Pulmonary fibrosis
C. Chronic obstructive pulmonary disease (COPD)
D. Gastroesophageal reflux disease (GERD)
E. Occupational asthma
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents to his GP complaining of bilateral breast enlargement over the past year. He denies any pain or tenderness. He takes no medications and reports no significant past medical history. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Prolactin level
B. Liver function tests
C. Fine needle aspiration
D. Serum testosterone and estradiol levels
E. Mammography
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