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Practice targeted AMC-style multiple-choice questions on general practice.

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Clinical aspects of mammary Paget's disease occurred on the thoracic wall where simple mastectomy was performed some years before.
Image by Monica Giovannini, Carmelo D'Atri, Quirino Piubello, Annamaria Molino CC BY-SA 2.0 · Source

A 72-year-old woman, status post mastectomy, presents with a lesion. What is the MOST appropriate initial diagnostic test?

A. Patch testing
B. Skin biopsy
C. Wood's lamp examination
D. KOH examination
E. Fungal culture
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 55-year-old man presents to his general practitioner with a six-month history of bilateral breast tenderness and swelling. He is otherwise asymptomatic, reporting no nipple discharge, skin changes, or palpable lumps. His medical history includes well-controlled hypertension on amlodipine. He denies illicit drug use or significant alcohol intake. On examination, the finding shown in the image is noted. Given this presentation, what is the most appropriate initial diagnostic step?

A. Advise lifestyle modification and review in three months.
B. Serum hormonal profile including testosterone, oestradiol, LH, FSH, prolactin, and hCG.
C. Referral for surgical consultation and potential biopsy.
D. Bilateral diagnostic mammography to rule out malignancy.
E. Ultrasound examination of the breast and axillary lymph nodes.
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A 67-year-old man with a history of hypertension and type 2 diabetes is scheduled for elective cholecystectomy due to symptomatic gallstones. During the preoperative assessment, he mentions experiencing mild chest discomfort during exertion over the past few weeks. What is the most appropriate next step in his preoperative management?

A. Start the patient on aspirin and beta-blockers immediately
B. Order a preoperative chest X-ray
C. Refer for a cardiology evaluation and possible stress testing
D. Proceed with surgery as planned with close intraoperative monitoring
E. Schedule an urgent coronary angiogram
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents to the emergency department with a 12-hour history of severe, constant left groin pain. He reports a bulge in his groin that has been present for several years, which he can usually reduce himself. However, today he has been unable to push it back in, and the pain has become excruciating. He denies any fever, nausea, or vomiting. On examination, his vital signs are stable: temperature 37.0°C, heart rate 88 bpm, blood pressure 130/80 mmHg, respiratory rate 16 breaths/min, and oxygen saturation 98% on room air. Abdominal examination is unremarkable. Palpation of the left groin reveals a firm, tender mass that is non-reducible. The overlying skin is erythematous, but there is no crepitus. A CT scan of the abdomen and pelvis is performed, and an axial slice is shown. Given the clinical scenario and the imaging findings, what is the MOST appropriate next step in management?

A. Order a repeat CT scan with intravenous contrast in 6 hours to assess for bowel ischemia
B. Prescribe oral analgesics and instruct the patient to follow up with his general practitioner in 24 hours
C. Surgical consultation for emergent operative intervention
D. Attempt manual reduction with intravenous sedation and analgesia
E. Administer broad-spectrum antibiotics and observe for improvement
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Figure 3 of paper: Alveolar echinococcosis in a patient with immunosuppression.

(a) Abdominal gray-scale US shows an abscess-like hepatic image.
(b) Axial unenhanced CT shows a typical aspect of pyogenic liver abscess.
Image by Wenya Liu, Éric Delabrousse, Oleg Blagosklonov, Jing Wang, Hongchun Zeng, Yi Jiang, Jian Wang, Yongde Qin, Dominique Angèle Vuitton, Hao Wen CC BY 4.0 · Source

A 58-year-old male presents with vague abdominal pain and unintentional weight loss. He has a history of working on a sheep farm. The provided imaging was obtained. Which of the following serological tests is MOST appropriate?

A. Amoebic serology
B. Hepatitis B surface antigen
C. Echinococcus IgG antibody
D. Strongyloides IgG antibody
E. Alpha-fetoprotein
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A 62-year-old male presents to his general practitioner with a six-month history of a painless swelling in his right groin. He reports that the swelling becomes more prominent when he strains or coughs and reduces when he lies down. On examination, a soft, reducible bulge is palpable in the right inguinal region. The bulge is felt to emerge medial to the inferior epigastric vessels. Which of the following is the most appropriate next step in management, according to current Australian guidelines?

A. Referral to a physiotherapist for core strengthening exercises.
B. Referral to a general surgeon for elective open or laparoscopic inguinal hernia repair.
C. Urgent referral to an emergency department for assessment of possible strangulation.
D. Reassurance and watchful waiting, with advice on lifestyle modifications.
E. Prescription of a truss to support the hernia.
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 62-year-old male presents with left lower quadrant pain, fever, and leukocytosis. A CT scan of the abdomen and pelvis is performed, the axial view is shown. What is the most appropriate next step in management?

A. Order a barium enema to assess for fistula
B. Prescribe oral antibiotics and a high-fiber diet
C. Perform a colonoscopy to rule out malignancy
D. Schedule elective sigmoid colectomy
E. Initiate intravenous antibiotics and bowel rest
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A 62-year-old postmenopausal woman presents to her general practitioner with complaints of severe hot flashes that significantly affect her quality of life. She has a history of breast cancer diagnosed three years ago, which was treated with surgery and chemotherapy. Her cancer was estrogen receptor-positive. She is currently on tamoxifen as part of her ongoing treatment. She is concerned about the use of hormone replacement therapy due to her cancer history. What is the most appropriate management option for her hot flashes?

A. Conjugated estrogens
B. Clonidine
C. Paroxetine
D. Black cohosh
E. Gabapentin
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 68-year-old male presents with new onset constipation and abdominal pain. The provided CT was obtained. What is the MOST likely long-term complication?

A. Toxic megacolon
B. Abscess formation
C. Stricture formation
D. Perforation
E. Fistula formation
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A 37-year-old lady presents with a sudden right-sided facial droop, with no ear symptoms or dysphagia. She is 16 weeks pregnant. What is the likely diagnosis?

A. Multiple Sclerosis
B. Schwannoma
C. Stroke
D. Ramsay Hunt syndrome
E. Bell's palsy
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A 62-year-old man presents to his general practitioner with a 6-month history of a bulge in his groin that appears when he strains or coughs. He reports mild discomfort but no severe pain. On examination, the GP identifies a soft, reducible mass in the right groin area that appears to emerge through the superficial inguinal ring when the patient coughs. The mass reduces spontaneously when the patient lies down. Which of the following is the most appropriate next step in management, according to Australian guidelines?

A. Urgent referral to the emergency department for strangulation risk
B. Referral to a general surgeon for elective repair
C. Referral for an abdominal CT scan to rule out other pathology
D. Reassurance and watchful waiting with lifestyle advice
E. Prescription of a truss to support the hernia
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for routine follow-up. He is asymptomatic. Review the image. What is the most appropriate next step in management?

A. Commence dual antiplatelet therapy
B. Repeat imaging in 6-12 months
C. Prescribe a statin
D. Initiate beta-blocker therapy
E. Schedule elective surgical repair
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash that started a few weeks ago. She reports that it began on her wrists and ankles and has now spread to her elbows and knees. She denies any new medications, travel, or changes in personal care products. On examination, you observe symmetrical, excoriated papules and plaques on her wrists, elbows, knees, and upper back. Some of the papules have small blisters. Which of the following is the most appropriate initial investigation?

A. Patch testing with a standard allergen series
B. Potassium hydroxide (KOH) examination of skin scraping
C. Serum IgE level
D. Skin biopsy for direct immunofluorescence
E. Viral culture of blister fluid
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A 62-year-old female has high blood pressure (162/97 mmHg) but is not concerned. She has white coat hypertension and declines 24-hour BP monitoring. What is the correct instruction about home blood pressure readings?

A. Check blood pressure immediately after waking up.
B. Check BP before daily medications.
C. Check blood pressure while talking or watching TV.
D. Check blood pressure only when feeling unwell.
E. Check blood pressure after food and exercise.
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with right groin pain and a palpable mass. He reports constipation and mild nausea. Vitals are stable. The provided image was obtained. What is the MOST appropriate next step in management?

A. Manual reduction attempt
B. Stool softeners and observation
C. Broad-spectrum antibiotics
D. Surgical consultation for emergent repair
E. Increase oral fluid intake and monitor
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents for a routine check-up. He has a history of smoking and hypertension, managed with lisinopril. He denies any abdominal pain, back pain, or lower extremity claudication. Physical exam is unremarkable. A contrast-enhanced CT scan of the abdomen is performed, the axial view is shown. What is the MOST appropriate next step in management?

A. Order a D-dimer to rule out acute aortic dissection
B. Referral to vascular surgery for elective repair
C. Initiate beta-blocker therapy to reduce wall stress
D. Repeat imaging in 6-12 months to monitor growth
E. Prescribe a statin to stabilize atherosclerotic plaques
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 48-year-old man presents with a 2-year history of progressive, tender breast enlargement causing significant distress. Initial investigations including liver function tests, renal function tests, and basic hormonal assays (LH, FSH, testosterone, oestradiol) were largely within normal limits, except for a mildly elevated oestradiol. He takes no regular medications and denies recreational drug use. He is otherwise well and his physical examination is unremarkable apart from the findings shown in the image. Considering the clinical presentation and the findings, what is the most appropriate next step in his management?

A. Order a CT scan of the abdomen and pelvis to exclude occult malignancy.
B. Initiate a trial of tamoxifen for 3-6 months.
C. Reassure the patient that this is benign and requires no further intervention.
D. Referral to a plastic or general surgeon for consideration of reduction mammoplasty.
E. Repeat hormonal assays including prolactin and hCG.
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 55-year-old woman with no palpable breast lumps presents for a routine screening mammogram. The image is shown. What is the MOST appropriate next step?

A. Stereotactic core biopsy
B. Ultrasound of the breast
C. Reassurance and routine follow-up in 1 year
D. Excisional biopsy
E. MRI of the breast
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A 45-year-old man presents to the general practice clinic with a 6-month history of progressive shortness of breath and a persistent dry cough. He works as a construction worker and has a 20-pack-year smoking history. On examination, he has clubbing of the fingers and fine inspiratory crackles at the lung bases. Pulmonary function tests show a restrictive pattern. A high-resolution CT scan of the chest reveals reticular opacities and honeycombing predominantly in the lower lobes. Which of the following is the most likely diagnosis?

A. Sarcoidosis
B. Hypersensitivity pneumonitis
C. Idiopathic pulmonary fibrosis
D. Asbestosis
E. Chronic obstructive pulmonary disease
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Umbilical hernia
Image by Ibrahim Husain Meraj CC BY-SA 4.0 · Source

A 14-month-old child is presented to the general practitioner by their parents, who are concerned about a noticeable protrusion around the navel. They report this bulge is more prominent when the child cries or strains but easily disappears when the child is relaxed or sleeping. There are no reports of pain, discomfort, changes in bowel habits, or feeding difficulties. The child is meeting all developmental milestones and appears well. On examination, vital signs are stable and within age-appropriate ranges. The abdomen is soft and non-tender, with no distension. The finding illustrated in the accompanying image is observed. Based on this clinical presentation and examination, what is the most appropriate initial management plan?

A. Refer the child urgently to a paediatric surgeon for immediate assessment and potential repair.
B. Recommend applying a specific binder or tape over the area to facilitate closure.
C. Provide reassurance to the parents regarding the benign nature of the finding and advise observation, explaining the high likelihood of spontaneous resolution by school age.
D. Advise the parents to present immediately to the nearest emergency department if the bulge is visible.
E. Order an abdominal ultrasound to assess the contents and size of the defect.
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A 55-year-old non-smoker with no known comorbidities has a consistent office BP of 155/98 mmHg. His 10-year CVD risk is calculated as low. According to Australian guidelines, what is the most appropriate initial management?

A. Recommend lifestyle modifications and review in 3-6 months
B. Investigate for secondary causes of hypertension
C. Initiate single antihypertensive therapy
D. Refer for ambulatory blood pressure monitoring
E. Initiate dual antihypertensive therapy
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Upright X-ray demonstrating small bowel obstruction
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 68-year-old male presents with abdominal distension and obstipation. An upright abdominal X-ray is performed. What is the MOST appropriate next step in management?

A. Stool softeners
B. Colonoscopy
C. Barium enema
D. Increase oral fluid intake
E. Surgical consultation
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A contrast enhanced CT scan demonstrating an abdominal aortic aneurysm of 4.8 * 3.8 cm
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 72-year-old man with a history of hypertension and hyperlipidemia presents for a routine health check. He is asymptomatic. A contrast-enhanced CT abdomen is performed, axial view shown. Besides optimizing medical management, what is the MOST appropriate next step?

A. Referral for immediate surgical repair
B. Prescribe a statin
C. Initiate aspirin therapy
D. Repeat imaging in 6-12 months
E. Order a D-dimer
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An incarcerated inguinal hernia as seen on CT
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 75-year-old male with a history of a reducible groin hernia presents with acute abdominal pain. The provided image was taken. What is the most likely complication?

A. Indirect hernia
B. Sliding hernia
C. Richter's hernia
D. Strangulation
E. Direct hernia
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old male presents with concerns about breast enlargement over the past year. He denies pain or nipple discharge. He takes no medications and reports no significant past medical history. Examination reveals the findings in the image. What is the MOST appropriate initial investigation?

A. Liver function tests
B. Prolactin level
C. Mammography
D. Serum testosterone and estradiol levels
E. Fine needle aspiration
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A 28-year-old woman presents to the clinic with a 2-week history of fever, night sweats, and a non-productive cough. She has recently returned from a trip to rural Queensland. On examination, she has crackles in the right upper lung field. A chest X-ray shows a cavitary lesion in the right upper lobe. What is the most likely diagnosis?

A. Tuberculosis
B. Lung abscess
C. Pulmonary embolism
D. Sarcoidosis
E. Pneumonia
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash on her elbows, knees, and scalp for the past 6 months. She reports that the itching is worse at night and after hot showers. She has tried over-the-counter hydrocortisone cream without relief. On examination, the GP notes symmetrical, excoriated papules and plaques on the extensor surfaces of her elbows and knees, as well as some scaling on her scalp. The patient also mentions a history of recurrent mouth ulcers. Which of the following is the MOST appropriate initial investigation to confirm the suspected diagnosis?

A. Skin biopsy for histopathology and direct immunofluorescence
B. Allergy testing (skin prick or RAST) for common environmental allergens
C. Full blood count (FBC) and liver function tests (LFTs)
D. Potassium hydroxide (KOH) examination of skin scrapings
E. IgA anti-endomysial antibody (EMA) and IgA tissue transglutaminase (tTG) antibody testing
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Diverticular disease
Image by James Heilman, MD CC BY-SA 4.0 · Source

A 62-year-old male with LLQ pain and mild fever has the CT abdomen shown. What is the MOST appropriate next step in management?

A. Colonoscopy to rule out malignancy
B. Oral antibiotics and outpatient follow-up
C. Stool culture to rule out infectious colitis
D. IV antibiotics and admission for observation
E. Surgical consultation for possible resection
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A 28-year-old woman presents to her GP with a 3-month history of amenorrhea. She reports occasional headaches and galactorrhea. She is not on any medications and has no significant past medical history. On examination, her vital signs are normal, and there are no visual field defects. A pregnancy test is negative. What is the most appropriate initial investigation?

A. MRI of the brain
B. Serum prolactin level
C. Thyroid function tests
D. FSH and LH levels
E. Pelvic ultrasound
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 58-year-old man presents with concerns about breast enlargement. Examination reveals the findings in the image. Which of the following is the MOST appropriate initial investigation?

A. Liver function tests
B. Medication review
C. Serum prolactin
D. Mammogram
E. Testicular ultrasound
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An Aboriginal woman, 48 years old, attends your general practice for a routine health check. She has a history of gestational diabetes and lives in a rural community. When discussing preventative health screening, which of the following is the MOST culturally appropriate and evidence-based approach?

A. Refer her to a specialist diabetes clinic in a major city for comprehensive assessment and management, ensuring she understands the importance of specialist care.
B. Recommend genetic testing for diabetes risk, as Aboriginal Australians have a higher prevalence of certain genetic predispositions.
C. Offer a comprehensive assessment including HbA1c, urine albumin creatinine ratio, blood pressure, BMI, smoking and alcohol use, and discuss cardiovascular risk, while acknowledging the impact of social determinants of health and incorporating her preferences for health management.
D. Focus primarily on diabetes screening with HbA1c testing, as she has a history of gestational diabetes, and provide written information about diabetes management.
E. Advise her to follow a standard Western diet and exercise plan to manage her diabetes risk, as these are proven effective strategies.
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old man presents with bilateral breast enlargement, as shown. He denies pain or nipple discharge. What is the MOST likely underlying cause?

A. Liver cirrhosis
B. Medication side effect
C. Hyperthyroidism
D. Klinefelter syndrome
E. Testicular cancer
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Facial eosinophilic granuloma. Red-brown nodule on the nose. Clearly visible follicular structures ("peau d'orange").
Image by Sand, Michael, et al. CC BY 2.0 · Source

A 50-year-old man presents with a slowly growing, asymptomatic nasal lesion. He reports no trauma or fever. Examination reveals the image shown. What is the MOST likely long-term outcome if left untreated?

A. Transformation to squamous cell carcinoma
B. Local tissue destruction
C. Metastatic spread
D. Spontaneous resolution
E. Development of systemic lupus erythematosus
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A 45-year-old man presents to the clinic with a 3-month history of persistent cough, night sweats, and weight loss. He has a history of smoking and works as a miner. On examination, he has decreased breath sounds and dullness to percussion over the right upper lobe. A chest X-ray shows a cavitary lesion in the right upper lobe. What is the most likely diagnosis?

A. Pulmonary tuberculosis
B. Chronic obstructive pulmonary disease (COPD)
C. Pneumonia
D. Lung cancer
E. Sarcoidosis
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A 32-year-old male presents to his general practitioner complaining of severe anal pain, especially during and after bowel movements. He also reports seeing bright red blood on the toilet paper. On examination, there is a visible tear in the anal mucosa at the 6 o'clock position. Which of the following is the MOST appropriate initial management strategy?

A. Stool softeners, topical analgesics, and sitz baths
B. Incision and drainage
C. High-fibre diet alone
D. Lateral internal sphincterotomy
E. Rubber band ligation
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A 55-year-old man presents to the clinic with a 3-month history of fatigue, weight loss, and night sweats. He has no significant past medical history. On examination, he has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal a hemoglobin level of 10 g/dL, white blood cell count of 15,000/mm³ with a predominance of lymphocytes, and a platelet count of 150,000/mm³. A lymph node biopsy is performed, showing small lymphocytic lymphoma. What is the most appropriate initial management for this patient?

A. Surgical excision of lymph nodes
B. Observation and regular follow-up
C. Immediate chemotherapy
D. Radiation therapy to affected lymph nodes
E. Initiation of corticosteroids
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Endoscopy image of colon adenocarcinoma in sigmoid colon.
Image by Unknown CC BY-SA 3.0 · Source

A 68-year-old male presents to his GP complaining of a change in bowel habit over the past 6 months. He reports increasing constipation alternating with episodes of diarrhea. He also mentions unintentional weight loss of approximately 5 kg during this period. He denies any family history of bowel cancer. A colonoscopy was performed, and a representative image is shown. Assuming the lesion is confirmed as malignant, what is the MOST appropriate next step in the management of this patient?

A. Referral for palliative care
B. Repeat colonoscopy in 3 years
C. CT scan of the chest, abdomen, and pelvis
D. Initiate adjuvant chemotherapy with FOLFOX
E. Administer a course of broad-spectrum antibiotics
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Diverticulitis in the left lower quadrant. There is outpouching of the colonic wall, wall thickening, and surrounding fat stranding.
Image by James Heilman, MD CC BY-SA 3.0 · Source

A 65-year-old man presents to his GP with a 2-day history of constant, dull aching pain in the left lower quadrant of his abdomen. He reports mild nausea but no vomiting. His bowel movements have been normal. He denies fever or chills. His past medical history includes well-controlled hypertension. On examination, he is afebrile (37.2°C), blood pressure is 135/85 mmHg, heart rate 72 bpm, respiratory rate 16 bpm. Abdominal examination reveals mild tenderness on deep palpation in the left iliac fossa, without guarding or rebound tenderness. Bowel sounds are normal. Digital rectal examination is unremarkable. Laboratory investigations show a white cell count of 10.5 x 10^9/L (normal range 4-11) and a C-reactive protein of 25 mg/L (normal <5). A CT scan of the abdomen and pelvis is performed (image provided). Considering the patient's clinical presentation and the findings demonstrated in the provided image, which of the following represents the most appropriate initial management strategy?

A. Initiate a course of oral antibiotics and provide analgesia for outpatient management.
B. Admit the patient for intravenous antibiotics and close observation.
C. Arrange for urgent surgical consultation for potential intervention.
D. Schedule a colonoscopy within the next 48 hours to assess the colonic mucosa.
E. Discharge the patient with only simple analgesia and advice on a low-fibre diet.
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Gynaecomastia
Image by ProloSozz CC BY-SA 4.0 · Source

A 62-year-old male presents with bilateral breast enlargement for 6 months. He denies pain, discharge, or skin changes. He reports taking saw palmetto for BPH. Examination reveals the findings in the image. What is the MOST likely cause?

A. Hyperthyroidism
B. Testicular cancer
C. Cirrhosis
D. Idiopathic
E. Medication side effect
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A 60-year-old man presents to his GP with a 3-month history of fatigue, weight loss, and night sweats. He has a history of smoking and hypertension. On examination, he has palpable lymphadenopathy in the cervical and axillary regions. Blood tests reveal anemia and elevated lactate dehydrogenase (LDH). What is the most appropriate next step in the investigation of this patient?

A. PET scan
B. Excisional lymph node biopsy
C. CT scan of the chest and abdomen
D. Fine needle aspiration of the lymph node
E. Bone marrow biopsy
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A 35-year-old Aboriginal woman presents for a routine health check. She reports feeling tired lately and sometimes short of breath on exertion. She has a history of type 2 diabetes diagnosed 5 years ago, managed with metformin 500mg twice daily, and untreated hypertension. On examination, her blood pressure is 145/90 mmHg. Urinalysis shows 2+ protein. Blood tests reveal creatinine 180 µmol/L, eGFR 35 mL/min/1.73m², HbA1c 8.5%, potassium 4.2 mmol/L. Given these findings, which of the following is the most appropriate initial management step?

A. Increase the dose of metformin.
B. Prescribe a loop diuretic for fluid overload.
C. Advise dietary protein restriction only.
D. Initiate an ACE inhibitor or ARB and optimise blood pressure control.
E. Refer immediately for renal biopsy.
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Mammogram microcalcifications in carcinoma in situ, CC, details
Image by Jmarchn CC BY-SA 3.0 · Source

A 62-year-old woman presents for routine mammography. The image is shown. What is the MOST appropriate next step?

A. Reassurance and routine screening
B. Stereotactic core biopsy
C. Ultrasound of the breast
D. MRI of the breast
E. Excisional biopsy
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A 55-year-old man presents to the clinic with a 3-month history of worsening cough, weight loss, and night sweats. He has a 30-pack-year smoking history and worked in construction for 20 years. On examination, he has clubbing of the fingers and decreased breath sounds in the right lower lung field. A chest X-ray shows a right lower lobe mass. What is the most appropriate next step in the management of this patient?

A. Order sputum cytology
B. Perform a PET scan
C. Refer for bronchoscopy
D. Obtain a CT scan of the chest
E. Start empirical antibiotics
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A man presents to his GP complaining of insomnia. He has a history of addiction but is currently doing well. His girlfriend recently left him, and he states he will kill her if he sees her again. What is the most appropriate initial management step?

A. Refer him for anger management.
B. Advise him that his feelings are normal and will improve with time.
C. Arrange for immediate psychiatric assessment.
D. Inform the police.
E. Prescribe diazepam for a short duration.
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Elective abdominal ultrasonography of a 64 year old woman with past colicky pain but no current pain. It shows a mildly dilated common bile duct with what appears to be a gallstone (black arrow). The green and blue dots are blood flow, since the exam is done as a Doppler ultrasound to distinguish the bile duct from blood vessels.
Image by Mikael Häggström CC0 1.0 · Source

A 64-year-old woman reports past episodes of transient right upper quadrant pain, now resolved. She is currently asymptomatic with normal liver function tests. An abdominal ultrasound was performed as part of her evaluation. Based on the findings from this imaging study and her clinical history, what is the most appropriate management recommendation?

A. Medical dissolution therapy with ursodeoxycholic acid
B. Observation and symptomatic management as needed
C. Magnetic resonance cholangiopancreatography (MRCP) for further evaluation
D. Endoscopic retrograde cholangiopancreatography (ERCP) for stone extraction
E. Elective cholecystectomy
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A 7-year-old boy is brought to the GP by his parents due to poor performance at school. Teachers report that he is inattentive, easily distracted, and frequently interrupts others. What is the most appropriate first-line treatment?

A. Methylphenidate
B. Atomoxetine
C. Observation
D. Behavioral therapy
E. Clonidine
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A 32-year-old woman presents to her general practitioner complaining of a persistent, intensely itchy rash that started a few weeks ago. She reports that it began on her wrists and ankles and has now spread to her elbows and knees. She denies any new medications, travel, or changes in personal care products. On examination, you observe symmetrical, intensely pruritic, violaceous, flat-topped papules and plaques on her wrists, ankles, and shins. Some of the lesions show fine, white lines on the surface. There are also a few small, similar lesions on her buccal mucosa. Which of the following is the most appropriate initial management?

A. Systemic corticosteroids and antifungal cream
B. Topical corticosteroids and antihistamines
C. Oral antibiotics and topical emollients
D. Referral to a rheumatologist for autoimmune workup
E. Cryotherapy to the affected areas
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A 55-year-old lady presents with a painless, white, lacy pattern on her buccal mucosa that has been present for several weeks. She feels well and has no significant medical history. What is the likely diagnosis?

A. Oral lichen planus
B. Leukoplakia
C. Squamous cell carcinoma
D. Oral candidiasis
E. Erythroplakia
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A 32-year-old male presents to his general practitioner with persistent anal pain and bleeding on defecation for the past 8 months. He reports a cycle of pain, relief after bowel movements, followed by throbbing pain lasting several hours. Examination reveals a visible anal fissure at the 6 o'clock position, along with a skin tag. Which of the following is the MOST appropriate next step in management, according to Australian guidelines?

A. Topical glyceryl trinitrate (GTN) ointment and stool softeners
B. Fibre supplementation and sitz baths
C. Botulinum toxin injection into the internal anal sphincter
D. Excision of the fissure and skin tag with advancement flap
E. Lateral internal sphincterotomy
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A 32-year-old woman presents to her general practitioner six weeks postpartum with distressing obsessive thoughts about accidentally harming her newborn. She reports spending excessive time checking on the baby and cleaning the nursery, which interferes with her ability to rest and care for herself. She denies any intent to harm her child and feels ashamed of these thoughts. Her past medical history is unremarkable, and she has no history of psychiatric disorders. On examination, she appears anxious but is cooperative and oriented. Which of the following is the most appropriate initial management strategy for her condition?

A. Cognitive-behavioral therapy (CBT) with exposure and response prevention
B. Reassurance and monitoring without immediate intervention
C. Referral to a psychiatrist for further evaluation
D. Initiation of selective serotonin reuptake inhibitor (SSRI) therapy
E. Prescribing benzodiazepines for immediate anxiety relief
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